Curcumin and ovarian cancer: preclinical avenues, not a proven benefit in patients
A review of 21 studies explores curcumin and its nanoformulations in preclinical models of ovarian cancer, without establishing their clinical efficacy.
Read the newsThe news feed
Recent studies and announcements, explained with the same rigor as our analyses: sources, context, and the limitations of the data.
The publication feed
Exercise and epilepsy: a pilot trial shows good adherence, not proven effectiveness
Four adults with epilepsy attended every session of a supervised aerobic exercise program. This small trial assesses feasibility, not effectiveness in reducing seizures.
Music and AI-generated suggestions: a signal for negative emotions, but not anxiety
An exploratory trial involving 113 Chinese students found fewer negative emotions with an intervention combining music and culturally adapted suggestions, with no detected difference in anxiety.
Motor-cognitive warm-ups: no demonstrated immediate benefit for jump landings
A crossover trial involving 18 athletes shows no established immediate benefit of motor-cognitive warm-ups for unplanned jump landings.
ADHD in children: promising digital interventions, but varying effects
A meta-analysis of 37 randomized trials suggests benefits for symptoms and cognition, without establishing their practical magnitude.
Type 1 diabetes: associations with the oral microbiota, but no validated biomarker
A review of 42 studies links poorer glycemic control to certain oral microbial changes, without establishing causality.
Coronary artery disease: microbiota metabolites associated with prognosis, without evidence of treatment benefit
A review of 18 prospective studies links certain microbiota metabolites to coronary prognosis, without demonstrating that an intervention improves health.
Bicarbonate and sprints: a trial in basketball players suggests an additional benefit, without quantifying it
In 40 trained basketball players, a four-week trial suggests a benefit from adding bicarbonate to sprint training. The size of the benefit and tolerability remain to be clarified.
Paeoniflorin and inflammation: promising mechanisms, little clinical evidence
A review explores the anti-inflammatory mechanisms of paeoniflorin. Clinical data remain limited, and its oral bioavailability is low.
Anxiety and depression in athletes: a meta-analysis highlights the limits of exercise’s protective effects
A review of 64 studies describes anxiety and depressive symptoms in athletes without a current injury, without establishing a comparison with non-athletes.
Fear of negative judgment is linked to social anxiety, with no evidence of causality
A meta-analysis of 143 studies confirms an association between fear of negative judgment and social anxiety, but cannot establish a causal link.
Trapezius pain: a trial detects no difference between two durations of magnetic stimulation
In 66 adults, two durations of magnetic stimulation combined with stretching produced similar results at four weeks, with no placebo group.
Child malnutrition: eligibility for referral is not enough to demonstrate a benefit
In Burkina Faso, a study detects no clear benefit from eligibility for nutritional referral. It does not assess treatment effectiveness.
Surgery and multiple chronic conditions: preoperative pathways remain understudied
A systematic review highlights the lack of data on preoperative pathways tailored to adults living with multiple chronic conditions.
Cholesterol and subarachnoid hemorrhage: no major link established
A review and a genetic analysis in UK Biobank do not support a major association between blood lipids and subarachnoid hemorrhage.
Pregnancy: an amaranth–chickpea flatbread improves nutritional indicators in a trial in Ethiopia
A trial in pregnant women with anemia reports better anthropometric indicators with an amaranth–chickpea flatbread, without demonstrating a benefit for the baby.
Mental health among trans adults: a meta-analysis estimates high prevalence rates, with substantial variation
A synthesis of 207 studies documents mental health among trans and gender-diverse adults, without establishing the causes of the difficulties observed.
Metals in freshwater fish in Brazil: a review highlights uneven exposure risks
A systematic review describes variable contamination of freshwater fish in Brazil, with exposure risks for populations that consume large amounts of fish.
Oral cancer: physical activity associated with better recovery, but evidence remains heterogeneous
A review of 24 studies suggests benefits for physical function and fatigue after oral cancer, without establishing an optimal program.
MRI and cognition: markers associated with cognitive impairment in small vessel disease
A review of 15 studies links white matter abnormalities to poorer cognitive performance, without establishing their reliability for early screening.