Recent studies and announcements, explained with the same rigor as our analyses: sources, context, and the limitations of the data.
A meta-analysis suggests that carotid or femoral ultrasound cannot replace cardiac CT to detect silent coronary atherosclerosis. The evidence remains of very low quality.
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A meta-analysis of 15 trials shows no significant reduction in fibrinogen or PAI-1 with probiotics or synbiotics. The evidence remains low-certainty.
A meta-analysis of 72 trials finds improved arterial dilation. The reduction in cardiovascular risk remains an estimate.
A meta-analysis of ten trials suggests modest improvements in quality of life and anxiety, but no established benefit for depression.
In 29 night workers, a pilot trial shows no significant improvement in daytime sleep with lemborexant compared with placebo.
A trial in 530 adults aged 50 and older supports simultaneous administration of two specific vaccines, without demonstrating equivalent clinical protection.
A protocol plans to compare remimazolam with propofol during spine surgery in the prone position. No results have been reported yet.
In adults aged 60 and older, a trial supports administering two vaccines together, without directly measuring protection against infections.
A review of 17 studies finds encouraging performance in predicting postpartum post-traumatic stress, without establishing clinical usefulness.
A review of 100 US studies describes gaps in access to GLP-1 agonists and SGLT2 inhibitors, without quantifying their magnitude in the available abstract.
A review of 92 trials suggests benefits of digital care for pain and functional limitations, but the evidence remains weak.
A trial in 30 female athletes reports changes in body composition with tangeretin, but the abstract does not allow the benefit over placebo to be quantified.
A trial in 48 military cadets reports improvements with Tabata, with or without cinnamon. The supplement’s added benefit remains uncertain.
A randomized trial observes changes in two markers related to mitochondria and antioxidant defenses, without establishing a clinical benefit.
A secondary analysis of a trial links microbiota functions to brain maturation in preterm infants, without demonstrating a neurological benefit.
A trial involving 84 people with irritable bowel syndrome found biological changes with zinc, but no significant improvement in sleep.
A meta-analysis links exercise to increased peripheral BDNF and improved depressive symptoms, without establishing an optimal dose.
A study of 20 healthy volunteers compares the forces and deformations associated with two lumbar manipulation techniques. It does not demonstrate a clinical benefit.
QUALINEURO-REHAB will evaluate a programme combining physical activity and cognitive training in people aged 8–25. No efficacy results have been presented yet.
A randomized trial finds a lower inflammatory response after opioid-free anesthesia with regional blocks, with no established lasting clinical benefit.
