Complex post-traumatic stress: widely varying estimates among displaced people
A meta-analysis documents complex post-traumatic stress among displaced people, without establishing a generalizable prevalence estimate.
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Recent studies and announcements, explained with the same rigor as our analyses: sources, context, and the limitations of the data.
The publication feed
Antihypertensives in care facilities: reducing treatment has no established clinical benefit
A review of three randomized trials shows that deprescribing reduces medication use and raises blood pressure, without establishing its effect on mortality.
Screens and obesity in young people: associations that may differ by sex
A review of 22 studies links screen time to obesity indicators in young people, without establishing causality or confirming differences between sexes.
Peripheral artery disease: motivational support under study to improve walking
An exploratory analysis of a pilot trial examines whether social context influences the outcomes of motivational support in patients with peripheral artery disease.
Cancer: review of European guidelines highlights gaps in psychological support
A review of 38 publications finds inconsistent recommendations, mainly focused on distress, anxiety and depression in adults.
Endometrial cancer: diet and lifestyle associated with lower incidence, with limited evidence
An overview of 21 reviews identifies associations between diet, lifestyle and endometrial cancer, without demonstrating a causal protective effect.
Ramadan and heart failure: a review finds no signal of increased risk, but uncertainties remain
A review of seven studies reports no increase in hospitalizations or mortality during Ramadan. It does not establish safety for everyone.
Premenstrual symptoms and academic difficulties: an association, not proven causation
A review of 11 studies links premenstrual symptoms to poorer well-being among female health sciences students, without establishing causation.
Type 2 diabetes: a self-management programme improves some markers without proving kidney protection
A Chinese randomised trial reports improvements in several markers in patients at risk of kidney disease. The clinical benefit remains to be established.
After a heart attack, evolocumab lowers LDL further in a small 12-week trial
In 90 patients after a heart attack, adding evolocumab to atorvastatin lowered LDL further, without demonstrating a clinical benefit in this trial.
Anxiety and depression in athletes: a meta-analysis highlights the limits of exercise’s protective effects
A review of 64 studies describes anxiety and depressive symptoms in athletes without a current injury, without establishing a comparison with non-athletes.
Child malnutrition: eligibility for referral is not enough to demonstrate a benefit
In Burkina Faso, a study detects no clear benefit from eligibility for nutritional referral. It does not assess treatment effectiveness.
Surgery and multiple chronic conditions: preoperative pathways remain understudied
A systematic review highlights the lack of data on preoperative pathways tailored to adults living with multiple chronic conditions.
Cholesterol and subarachnoid hemorrhage: no major link established
A review and a genetic analysis in UK Biobank do not support a major association between blood lipids and subarachnoid hemorrhage.
Pregnancy: an amaranth–chickpea flatbread improves nutritional indicators in a trial in Ethiopia
A trial in pregnant women with anemia reports better anthropometric indicators with an amaranth–chickpea flatbread, without demonstrating a benefit for the baby.
Mental health among trans adults: a meta-analysis estimates high prevalence rates, with substantial variation
A synthesis of 207 studies documents mental health among trans and gender-diverse adults, without establishing the causes of the difficulties observed.
Metals in freshwater fish in Brazil: a review highlights uneven exposure risks
A systematic review describes variable contamination of freshwater fish in Brazil, with exposure risks for populations that consume large amounts of fish.
RSV and shingles vaccines: antibody responses preserved with simultaneous administration
A trial in 530 adults aged 50 and older supports simultaneous administration of two specific vaccines, without demonstrating equivalent clinical protection.
RSV and pneumococcal vaccines: comparable immune responses when administered together
In adults aged 60 and older, a trial supports administering two vaccines together, without directly measuring protection against infections.
Post-traumatic stress after childbirth: promising predictive models, but still limited validation
A review of 17 studies finds encouraging performance in predicting postpartum post-traumatic stress, without establishing clinical usefulness.